Thermo Fisher Scientific IFI6 Polyclonal Antibody
Human IFI6 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC에 사용 가능. 합성 펩타이드(AA 5–55)로부터 유래. 액상 형태, 1 mg/mL 농도, PBS/glycerol buffer에 보관. -20°C에서 저장, 연구용 전용.
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- PA599824
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 | View 1 publication |
| Immunohistochemistry (IHC) | – | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human IFI6 (Accession P09912), corresponding to amino acid residues A5–G55 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818757 |
Product Specific Information
Antibody detects endogenous levels of total IFI6.
Target Information
G1P3, also known as Interferon alpha-inducible protein 6 (IFI6) and Interferon-induced protein 6-16, is a 130 amino acid member of the IFI6 family of proteins. Localized to the mitochondria, G1P3 is a multi-pass membrane protein that is induced by IFN-α2β. G1P3 plays a major role in the apoptosis pathway by acting as a cell survival protein inhibiting caspase-3 activity, thereby antagonizing apoptosis. It has been implicated in tumorigenesis and is under study for therapeutic applications aimed at reducing G1P3-mediated antiapoptotic signals in myeloma and other malignancies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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