Thermo Fisher Scientific KRT84 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:3,000

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human KRT84(Accession Q9NSB2), corresponding to amino acid residues G550-Y600. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:KRT84,uniProtId:Q9NSB2-1,ncbiNodeId:9606,antigenRange:550-600,antigenLength:600,antigenImageFileName:PA5-99825_KRT84_Q9NSB2-1_Rabbit.svg,antigenImageFileNamePDP:PA5-99825_KRT84_Q9NSB2-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2818758

Product Specific Information

Antibody detects endogenous levels of total KRT84.

Target Information

The Keratin multigene family is made of soft epithelial cytokeratins and hard hair Keratins. While the epithelial cytokeratins are involved in the layering and formation of epithelia, the hair Keratins are responsible for creating nails and hair. There are two types of Keratins: the acidic class I Keratin proteins and the basic/neutral class II Keratin proteins. Keratin 84, also known as KRT84, HB4 or KRTHB4, is a 600 amino acid protein that is expressed in hair follicles. Keratin 84 is a basic/neutral type II Keratin protein which heterodimerizes with type I Keratins to create hair and nails. The gene encoding Keratin 84 maps to human chromosome 12 which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis and Kniest dysplasia.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.