Thermo Fisher Scientific Bit1 Polyclonal Antibody
Bit1 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC/IF에 사용 가능. Human 및 Mouse 시료에 반응하며, 항원 친화 크로마토그래피로 정제됨. PBS 버퍼에 0.02% sodium azide 포함, 2–8°C 보관 권장.
- 카탈로그번호
- PA520168
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Bit1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–4 µg/mL |
| Immunohistochemistry (IHC) | 10 µg/mL |
| Immunocytochemistry (ICC/IF) | 20 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 16 amino acid peptide from near the center of human Bit1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long term storage store at -20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11152284 |
Product Specific Information
- Suggested positive control: Daudi cell lysate
- PA5-20168 can be used with blocking peptide PEP-0285
Target Information
The protein encoded by this gene is a mitochondrial protein with two putative domains: an N-terminal mitochondrial localization sequence and a UPF0099 domain.
In vitro assays suggest that this protein possesses peptidyl-tRNA hydrolase activity, releasing the peptidyl moiety from tRNA to prevent accumulation of dissociated peptidyl-tRNA, which could reduce translation efficiency.
This protein also plays a role in regulating cell survival and death, promoting survival as part of an integrin-signaling pathway for cells attached to the extracellular matrix.
Mutations in this gene are associated with intellectual disability, postnatal microcephaly, progressive cerebellar atrophy, hearing impairment, polyneuropathy, failure to thrive, and organ fibrosis with exocrine pancreas insufficiency.
Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.