Thermo Fisher Scientific CLOCK Monoclonal Antibody (OTI1G3), TrueMAB
인간 CLOCK 단백질을 인식하는 마우스 단클론 항체로, Western blot과 IHC(Paraffin)에 적합합니다. 고순도 친화 크로마토그래피 정제, 동결건조 형태로 제공되며 보존제 무첨가 PBS 버퍼에 함유되어 있습니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1G3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–285 of human CLOCK produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
CLOCK encodes a transcription factor belonging to the basic helix-loop-helix (bHLH) family.
Polymorphisms in this protein are associated with circadian rhythm sleep disorders.
In mice, CLOCK acts as a circadian regulator forming a heterodimer with aryl hydrocarbon receptor nuclear translocator-like protein to activate transcription of the period 1 gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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