Thermo Fisher Scientific CLOCK Monoclonal Antibody (OTI2B12), TrueMAB
CLOCK 단백질을 인식하는 Mouse monoclonal 항체로, Western blot에 최적화되어 있습니다. Human 시료에 반응하며, Lyophilized 형태로 제공됩니다. 재구성 후 1 mg/mL 농도로 사용 가능하며, 연구용으로만 사용됩니다.
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Applications
- Western Blot (WB): 1:2,000 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2B12 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–285 of human CLOCK produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | –20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The CLOCK gene encodes a basic helix-loop-helix (bHLH) transcription factor involved in circadian rhythm regulation.
Polymorphisms in this gene are associated with circadian rhythm sleep disorders.
In mice, the homologous protein acts as a circadian regulator forming a heterodimer with aryl hydrocarbon receptor nuclear translocator-like protein to activate transcription of Period 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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