Thermo Fisher Scientific CLOCK Monoclonal Antibody (OTI4E12), TrueMAB
인간 CLOCK 단백질(aa 1-285)을 인식하는 Mouse IgG1 단클론 항체로 Western blot에 최적화됨. 동결건조 형태로 제공되며, PBS 및 trehalose buffer에 보관. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4E12 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–285 of human CLOCK produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The CLOCK gene encodes a protein belonging to the basic helix-loop-helix (bHLH) family of transcription factors. Polymorphisms in this protein are associated with circadian rhythm sleep disorders. In mice, CLOCK acts as a circadian regulator and forms a heterodimer with aryl hydrocarbon receptor nuclear translocator-like protein to activate transcription of mouse period 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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