Thermo Fisher Scientific CLOCK Monoclonal Antibody (OTI2H7), TrueMAB
CLOCK 단백질을 인식하는 Mouse monoclonal antibody로, Western blot과 IHC(P)에서 검증됨. Human 시료에 반응하며, Lyophilized 형태로 제공. 재구성 후 1 mg/mL 농도로 사용 가능. 연구용으로 circadian rhythm 관련 단백질 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2H7 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–285 of human CLOCK produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The CLOCK gene encodes a protein belonging to the basic helix-loop-helix (bHLH) family of transcription factors.
Polymorphisms in this gene are associated with circadian rhythm sleep disorders.
In mice, a homologous protein functions as a circadian regulator, acting as a transcription factor that forms a heterodimer with the aryl hydrocarbon receptor nuclear translocator-like protein to activate transcription of the mouse period 1 gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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