Thermo Fisher Scientific DSCR1 Monoclonal Antibody (1B1)
DSCR1 단백질을 인식하는 Mouse monoclonal antibody (Clone 1B1). Western blot, ICC/IF, ELISA 등에 사용 가능. 인간 RCAN1 단백질과 반응하며, Affinity chromatography로 정제된 액상 형태. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| ELISA | 0.3 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1B1 |
| Immunogen | DSCR1 (AAH02864, 1–100 a.a.) partial recombinant protein with GST tag (MW of GST tag alone: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MEEVDLQDLP SATIACHLDP RVFVDGLCRA KFESLFRTYD KDITFQYFKS FKRVRINFSN PFSAADARLQ LHKTEFLGKE MKLYFAQTLH IGSSHLAPPN
Target Information
The RCAN1 protein interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development.
This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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