Thermo Fisher Scientific TSC22D3 Monoclonal Antibody (3A5)
TSC22D3 단백질을 인식하는 Mouse Monoclonal Antibody (Clone 3A5). Western blot, IHC, ICC/IF, ELISA, IP 등 다양한 응용 가능. Human 종에 반응하며 PBS buffer에 보존, 보존제 없음. 연구용으로만 사용.
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Thermo Fisher Scientific TSC22D3 Monoclonal Antibody (3A5)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 3 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| ELISA | 0.03 ng/mL |
| Immunoprecipitation (IP) | 1–5 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3A5 |
| Immunogen | TSC22D3 (NP_932174, 1–97 a.a) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MAQSKLDCRS PVGLDCCNCC LDLAHRSGLQ RGSSGENNNP GSPTVSNFRQ LQEKLVFENL NTDKLNSIMR QDSLEPVLRD PCYLINEGIC NRNIDQT
Target Information
The TSC22 domain family member 3 protein (TSC22D3) is a leucine zipper protein that functions as a transcriptional regulator. Its expression is stimulated by glucocorticoids and IL-10, playing a key role in anti-inflammatory and immunosuppressive responses.
TSC22D3 interacts with and inhibits NF-Kappa-B and AP-1, acts as a transcriptional co-activator for nuclear receptors and NF-Kappa-B, and is involved in mesenchymal stem cell differentiation toward osteoblasts and bone formation.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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