Thermo Fisher Scientific DSCR1 Monoclonal Antibody (1G7)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

10 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

1G7

Immunogen

DSCR1 (AAH02864, 1 a.a. approximately 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:RCAN1,uniProtId:P53805-1,ncbiNodeId:9606,antigenRange:1-100,antigenLength:252,antigenImageFileName:H00001827-M01A_RCAN1_P53805-1_House_mouse.svg,antigenImageFileNamePDP:H00001827-M01A_RCAN1_P53805-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Storage buffer

ascites

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: MEEVDLQDLP SATIACHLDP RVFVDGLCRA KFESLFRTYD KDITFQYFKS FKRVRINFSN PFSAADARLQ LHKTEFLGKE MKLYFAQTLH IGSSHLAPPN

Target Information

The RCAN1 protein interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.