Thermo Fisher Scientific TSC22D3 Monoclonal Antibody (2B2)
TSC22D3 단백질을 표적으로 하는 Mouse IgG2a 단클론 항체로, Western blot과 ELISA에 적합. 인간 시료에 반응하며 친화 크로마토그래피로 정제됨. PBS(pH 7.4) 용액 형태로 제공되며 방부제 없음. 연구용으로만 사용 가능.
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Thermo Fisher Scientific TSC22D3 Monoclonal Antibody (2B2)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 0.3 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2B2 |
| Immunogen | TSC22D3 (AAH18148, 1–77 a.a.) full-length recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MDLVKNHLMY AVREEVEILK EQIRELVEKN SQLERENTLL KTLASPEQLE KFQSCLSLEE PAPESPQVPE APGGSAV
Target Information
TSC22 domain family member 3 protein (TSC22D3) is a leucine zipper protein that functions as a transcriptional regulator. Its expression is stimulated by glucocorticoids and IL-10, playing a key role in anti-inflammatory and immunosuppressive mechanisms.
TSC22D3 interacts with and inhibits NF-Kappa-B and AP-1 signaling pathways. It also acts as a transcriptional co-activator for nuclear receptors and NF-Kappa-B, and is involved in mesenchymal stem cell differentiation toward osteoblasts and bone formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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