Thermo Fisher Scientific GPM6A Polyclonal Antibody
Rabbit polyclonal antibody targeting human GPM6A protein. Validated for Western blot applications. Reacts with human, mouse, and rat; predicted cross-reactivity with other mammals. Affinity-purified, liquid form, suitable for research use only.
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Applications
- Western Blot (WB): 0.5–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptides corresponding to Human GPM6A (aa 257–274, 2–11) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA, 30% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at −20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2633216 |
Product Specific Information
These polyclonal antibodies are of rabbit origin, developed by immunizing animals with specific proteins or peptides. The antibody is purified by affinity chromatography and tested for performance in relevant research applications.
Developed for Research Use Only and classified as non-hazardous and non-infectious.
Predicted to react with Monkey, Horse, Bovine, and Dog.
Target Information
Neuronal membrane glycoprotein M6-a (GPM6A) is encoded by the GPM6A gene in humans. It is involved in neuronal differentiation, migration of neuronal stem cells, and neuronal plasticity.
GPM6A contributes to neurite and filopodia outgrowth, filopodia motility, and possibly synapse formation.
Its activity involves MAPK and Src signaling pathways, and may regulate NGF-dependent Ca²⁺ influx, endocytosis, and intracellular trafficking of GPCRs, enhancing internalization and recycling of mu-type opioid receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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