Thermo Fisher Scientific HTR2B Polyclonal Antibody
Rabbit polyclonal antibody targeting HTR2B for research use. Validated in WB and ICC/IF applications. Affinity purified, unconjugated, liquid form. Reacts with human and predicted cross-reactivity with horse, pig, and cat.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptides corresponding to Human HTR2B (aa 285–304, 468–481) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA, 30% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2633218 |
Product Specific Information
These polyclonal antibodies are of rabbit origin and developed by immunizing animals with proteins or peptides. The antibody is affinity purified from rabbit sera and tested for functionality in various research applications.
Developed for Research Use Only, non-hazardous and non-infectious.
This antibody is predicted to react with Horse, Pig, and Cat.
Target Information
HTR2B is a G-protein coupled receptor for 5-hydroxytryptamine (serotonin). It functions as a receptor for various ergot alkaloid derivatives and psychoactive substances. Ligand binding induces a conformational change that triggers signaling via G proteins and modulates downstream effectors.
HTR2B plays a role in pain perception and behavioral regulation, and is required for normal proliferation of embryonic cardiac myocytes and heart development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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