Thermo Fisher Scientific Gephyrin Polyclonal Antibody
Rabbit polyclonal antibody targeting human Gephyrin (aa 1–220). Validated for WB and ICC/IF. Affinity purified and supplied in PBS buffer with BSA and glycerol. Suitable for neuroscience and molybdenum cofactor biosynthesis research.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Protein corresponding to Human GEPHYRIN (aa 1–220) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA, 30% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2633204 |
Product Specific Information
These polyclonal antibodies are of rabbit origin, developed by immunizing animals with specific proteins or peptides. The antibody is purified by affinity chromatography from rabbit sera and tested for functionality in relevant research applications.
Developed for Research Use Only and is non-hazardous or non-infectious.
Predicted to react with Monkey, Rat, Mouse, and Chicken.
Target Information
Gephyrin is a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high-affinity binding to receptor subunit domains and tubulin dimers. In non-neuronal tissues, it is required for molybdenum cofactor biosynthesis.
Mutations in this gene may be associated with hyperplexia and molybdenum cofactor deficiency.
Multiple alternatively spliced transcript variants encoding different isoforms have been described, though the full-length nature of all variants is not fully known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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