Thermo Fisher Scientific Phospho-STAT5A/B (Tyr694) Polyclonal Antibody
Phospho-STAT5A/B (Tyr694) 특이적 폴리클로날 항체로 Western blot, IHC, ELISA 등 다양한 응용 가능. 인간, 마우스, 랫트 반응성. 고순도 친화 크로마토그래피 정제, 액상 형태로 제공. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:100–1:500 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:100–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphorylated peptide around Y694 of human STAT5 (NP_003143.2 / NP_036580.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.45 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914884 |
Product Specific Information
- Positive test controls include: K562
- Immunogen sequence: DGYVK
Target Information
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by receptor-associated kinases, then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators.
This protein mediates responses to ligands such as IL-2, IL-3, IL-7, GM-CSF, erythropoietin, thrombopoietin, and various growth hormones. Activation of this protein in myeloma and lymphoma associated with TEL/JAK2 gene fusion is independent of cell stimulus and is essential for tumorigenesis. The mouse counterpart induces expression of BCL2L1/BCL-X(L), suggesting anti-apoptotic function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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