Thermo Fisher Scientific IL17RD Recombinant Rabbit Monoclonal Antibody (010)
Human IL17RD 단백질에 특이적인 재조합 토끼 모노클로날 항체로, ELISA에 최적화되어 높은 특이성과 민감도를 제공합니다. 동물 유래 성분이 없는 포뮬레이션으로 로트 간 일관성이 우수하며, 단기간 4°C 보관 및 장기간 -20°C 보관이 가능합니다.
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Applications
ELISA
- Tested Dilution: 1:5,000–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 010 |
| Immunogen | Recombinant Human IL17RD protein (Met1–Arg299) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2786261 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. These systems are developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select optimal candidates for production.
Advantages of recombinant rabbit monoclonal antibodies:
- Better specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
This antibody has specificity for Human IL17RD/SEF.
Target Information
Feedback inhibitor of fibroblast growth factor (FGF)-mediated Ras-MAPK signaling and ERK activation. May inhibit FGF-induced FGFR1 tyrosine phosphorylation. Regulates nuclear ERK signaling by blocking nuclear translocation of activated ERK without inhibiting cytoplasmic phosphorylation. Mediates JNK activation and may be involved in apoptosis. Might play a role in early stages of fate specification of GnRH-secreting neurons.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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