Thermo Fisher Scientific CTU1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human CTU1. Recombinant protein control fragment (Product #RP-99105). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CTU1,uniProtId:Q7Z7A3-1,ncbiNodeId:9606,antigenRange:77-151,antigenLength:348,antigenImageFileName:PA5-62843_CTU1_Q7Z7A3-1_Rabbit.svg,antigenImageFileNamePDP:PA5-62843_CTU1_Q7Z7A3-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2640243

Product Specific Information

Immunogen sequence: RLGISLQLVA VDEGIGGYRD AALAAVRRQA ARWELPLTVV AYEDLFGGWT MDAVARSTAG SGRSRSCCTF CGVLR

Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 93%.

Target Information

Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.