Thermo Fisher Scientific BMF Monoclonal Antibody (OTI7B3), TrueMAB
인간 BMF 단백질을 인식하는 마우스 단클론 항체로, Western blot에 적합합니다. 무보존제, 동결건조 형태이며 PBS 버퍼에 트레할로스 포함. 연구용으로만 사용되며 재구성 및 탈염 후 결합 실험에 활용 가능합니다.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7B3 |
| Immunogen | Full length human recombinant protein of human BMF (NP_001003940) produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of about 1 mg/mL.
For conjugation experiments, perform an additional round of desalting using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The BMF protein belongs to the BCL2 family, which regulates apoptosis through hetero- or homodimer formation.
It contains a BH3 domain and binds BCL2 proteins, functioning as an apoptotic activator.
BMF is sequestered to myosin V motors via dynein light chain 2, aiding in intracellular damage sensing and apoptosis initiation.
Alternative splicing generates multiple isoforms.
For Research Use Only.
Not for use in diagnostic procedures or resale without authorization.
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