Thermo Fisher Scientific Phospho-CDCP1 (Tyr743) Polyclonal Antibody
CDCP1 단백질의 Tyr743 인산화 형태를 특이적으로 검출하는 폴리클로날 항체. 인간, 마우스, 랫에서 반응하며 Western blot에 적합. 고순도 정제 및 안정한 PBS/glycerol 저장용액 제공. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CDCP1 (Accession Q9H5V8), corresponding to amino acid residues around phosphorylated Tyr743 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2816704 |
Product Specific Information
Antibody detects endogenous levels of CDCP1 only when phosphorylated at Tyr743.
Target Information
CDCP1 is a transmembrane protein containing three extracellular CUB domains. It is found to be overexpressed in colon and lung cancers. Its expression level is correlated with the metastatic ability of carcinoma cells. CDCP1 is located on the cell surface and has been shown to be tyrosine phosphorylated in a cancer cell line. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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