Thermo Fisher Scientific Interleukin-2 (IL-2) Monoclonal Antibody (IL2/4988)
Human IL-2 단백질을 인식하는 Mouse monoclonal antibody (Clone IL2/4988). IHC(P), IHC(PFA), Peptide Array에 사용 가능. Protein A/G로 정제된 액상 형태, 1 mg/mL 농도. 연구용으로만 사용.
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- 3558-MSM8-P1ABX
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
Peptide Array (Array)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | IL2/4988 |
| Immunogen | Recombinant fragment (around aa 21–153) of human IL2 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Interleukin 2 (IL-2) is an immuno-modulatory cytokine that plays a crucial role in the proliferation of activated T cells, and differentiation of B cells, natural killer cells, monocytes, and macrophages. IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL-4) and interleukin 7 (IL-7). The expression of the IL-2 gene in mature thymocytes is monoallelic, representing an unusual regulatory mode for precise gene expression. Disruption of a similar gene in mice leads to an ulcerative colitis-like disease, indicating its essential role in immune response to antigenic stimuli.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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