Thermo Fisher Scientific NQO1 Monoclonal Antibody (4D12)
NQO1 단백질을 검출하는 Mouse monoclonal antibody (Clone 4D12). Western blot, IHC, Flow cytometry, ELISA 등 다양한 응용에 사용 가능. Human 및 Mouse 시료에 반응. 장기 보관 시 -20°C에서 안정적으로 유지.
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Thermo Fisher Scientific NQO1 Monoclonal Antibody (4D12)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4D12 |
| Immunogen | Purified recombinant fragment of human NQO1 expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_11152501 |
Product Specific Information
MA5-15926 targets NQO1 in indirect ELISA, FACS, IHC, and WB applications, showing reactivity with human samples.
The immunogen is a purified recombinant fragment of human NQO1 expressed in E. coli.
MA5-15926 detects NQO1 with a predicted molecular weight of approximately 31 kDa.
Target Information
NQO1 is a member of the NAD(P)H dehydrogenase (quinone) family and acts as a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones, preventing the formation of radical species.
Altered expression of NQO1 has been observed in various tumors and is associated with Alzheimer’s disease (AD).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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