Thermo Fisher Scientific NQO1 Monoclonal Antibody (4D12)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:1,000

-

Flow Cytometry (Flow)

1:200-1:400

-

ELISA (ELISA)

1:10,000

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

4D12

Immunogen

Purified recombinant fragment of human NQO1 expressed in E. Coli.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

Conc. Not Determined

Storage buffer

ascites

Contains

0.03% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_11152501

Product Specific Information

MA5-15926 targets NQO1 in indirect ELISA, FACS, IHC, and WB applications and shows reactivity with Human samples.

The MA5-15926 immunogen is purified recombinant fragment of human NQO1 expressed in E. Coli. .

MA5-15926 detects NQO1 which has a predicted molecular weight of approximately 31kDa.

Target Information

NQO1 is a member of the NAD(P)H dehydrogenase (quinone) family and a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. NQO1s enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Altered expression of the protein has been seen in many tumors and is also associated with Alzheimers disease (AD).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.