Thermo Fisher Scientific NF-H Monoclonal Antibody (8H10)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

8H10

Immunogen

Purified recombinant fragment of human NEFH (amino acids: 968-1020) expressed in E. Coli. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:NF-H,uniProtId:P12036-1,ncbiNodeId:9606,antigenRange:968-1020,antigenLength:1026,antigenImageFileName:MA5-17134_NF-H_P12036-1_House_mouse.svg,antigenImageFileNamePDP:MA5-17134_NF-H_P12036-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein G

Storage buffer

PBS

Contains

0.05% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2538605

Product Specific Information

MA5-17134 targets NEFH in IHC, pep-ELISA, and WB applications and shows reactivity with Human samples.

The MA5-17134 immunogen is purified recombinant fragment of human NEFH (amino acids: 968-1020) expressed in E. Coli.

MA5-17134 detects NEFH which has a predicted molecular weight of approximately 112.4kDa.

Target Information

Involved in the maintenance of neuronal caliber, neurofilaments are the intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H. Like most other intermediate filament proteins (IFPs), the expression of the different neuronal IFPs is both tissue-specific and developmentally regulated. NF-H has an important role in mature axons and is involved in amyotrophic lateral sclerosis (ALS).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.