Thermo Fisher Scientific GRB2 Chimeric Recombinant Mouse Monoclonal Antibody (SAIC-19D-1F4)

Applications

Tested Dilution

Publications

Western Blot (WB)

Assay-dependent

-

Mass Spectrometry (MS)

Assay-dependent

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1, kappa

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

SAIC-19D-1F4

Immunogen

Peptide FGNDVQHFK, derived from the Growth factor receptor-bound protein 2, conjugated to KLH. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GRB2,uniProtId:P62993-1,ncbiNodeId:9606,antigenRange:101-109,antigenLength:217,antigenImageFileName:MA5-47896_GRB2_P62993-1_House_mouse.svg,antigenImageFileNamePDP:MA5-47896_GRB2_P62993-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS

Contains

0.02% ProClin 300

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_3074340

Product Specific Information

Specificity: Recognises human GRB2.

Target Information

GRB 2 protein contains one SH2 domain flanked on both sides by an SH3 domain. In response to EGF, GRB 2 binds, through its SH3 domains, to the guanine nucleotide exchange factor, Sos. The GRB 2-Sos complex then binds the EGF receptor. These interactions play a critical role in the activation of the p21 ras signaling pathway.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.