Thermo Fisher Scientific SEPT5 Chimeric Recombinant Rabbit Monoclonal Antibody (SP18)
SEPT5 단백질을 인식하는 Thermo Fisher Scientific의 재조합 토끼 단일클론 항체(SP18). Western blot, IHC, ELISA에 사용 가능하며 CDCrel-1 특이적 반응성을 가짐. HEK293 발현 시스템에서 생산, Protein A로 정제된 액상 형태로 제공.
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Thermo Fisher Scientific SEPT5 Chimeric Recombinant Rabbit Monoclonal Antibody (SP18)
Applications and Tested Dilution
- Western Blot (WB): Assay-dependent
- Immunohistochemistry (IHC): Assay-dependent
- ELISA: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rabbit, Rat |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SP18 |
| Immunogen | Immunoprecipitate from human brain |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3074332 |
Product Specific Information
- Specificity: This antibody recognizes CDCrel-1 and does not cross-react with CDCrel-2.
Target Information
This gene belongs to the septin family of nucleotide-binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved across species (yeast, Drosophila, mouse) and play roles in cytoskeletal organization.
Disruption of septin function affects cytokinesis, producing multinucleate or polyploid cells.
The SEPT5 gene is mapped to chromosome 22q11, a region associated with DiGeorge and velocardiofacial syndromes.
Translocation with the MLL gene has been reported in acute myeloid leukemia.
Two transcripts (2.2 kb major form, 3.5 kb minor form) are observed, differing by polyadenylation signal usage.
An alternatively spliced transcript variant with a different 5′ end has also been identified but not fully characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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