Thermo Fisher Scientific Calreticulin Recombinant Rabbit Monoclonal Antibody (SAIC-16D-6B9)
Calreticulin 단백질을 인식하는 토끼 유래 재조합 단클론 항체. Western blot, ICC/IF, Flow cytometry, ELISA, MS 등에 사용 가능. Human 반응성, Protein A 정제, 1 mg/mL 농도. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | Assay-dependent | |
| Immunocytochemistry (ICC/IF) | 1:100 | |
| Flow Cytometry (Flow) | 1:100 | |
| ELISA | Assay-dependent | |
| Mass Spectrometry (MS) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SAIC-16D-6B9 |
| Immunogen | Peptide GLQTSQDAR, derived from the calcium-binding protein chaperone Calreticulin, conjugated to KLH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_3074339 |
Product Specific Information
Specificity: Recognises human CALR.
Target Information
Calreticulin (CALR) is a calcium-binding chaperone that promotes folding, oligomeric assembly, and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. As a lectin, Calr interacts transiently with most monoglucosylated glycoproteins synthesized in the ER. It also interacts with the DNA-binding domain of NR3C1 to mediate nuclear export and may regulate maternal gene expression and oocyte maturation through calcium homeostasis control.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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