Thermo Fisher Scientific Cytokeratin 10 (Suprabasal Epithelial Marker) Monoclonal Antibody (DE-K10)
Cytokeratin 10을 인식하는 단클론 항체(DE-K10)로, 상피세포의 상층부 표지에 사용됩니다. IHC(P) 및 IHC(PFA) 실험에 적합하며, 인간, 개, 고양이 조직 반응성이 있습니다. 단백질 A/G 정제, 보존제 없음, -20°C 보관.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Cat, Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | DE-K10 |
| Immunogen | Cytoskeletal preparation extracted from human ectocervical epithelium |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Cytokeratins (CK) are intermediate filaments found in epithelial cells, both in keratinizing tissues (e.g., skin) and non-keratinizing cells (e.g., mesothelial cells). Although not typical endothelial markers, some microvascular endothelial cells also express cytokeratins.
There are at least 20 different CKs with molecular weights between 40–70 kDa and isoelectric points of 5–8.5, identifiable by two-dimensional gel electrophoresis.
Cytokeratins are divided into two classes: type I (acidic) and type II (basic) polypeptides. Each epithelial cell expresses at least one member from each class.
Monoclonal antibodies against cytokeratin proteins serve as useful markers for tumor identification and classification.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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