Thermo Fisher Scientific Cytokeratin 10 (Suprabasal Epithelial Marker) Monoclonal Antibody (KRT10/844)
Cytokeratin 10 단백질을 인식하는 Mouse Monoclonal Antibody로, Human 및 Mouse 시료에서 사용 가능. Western blot과 IHC에 적합하며, Protein A/G로 정제된 액상 형태. 4°C 보관, 연구용으로만 사용.
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | KRT10/844 |
| Immunogen | Recombinant full-length human KRT10 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage conditions | 4°C, do not freeze |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
Cytokeratins (CK) are intermediate filaments found in epithelial cells, both keratinizing (e.g., skin) and non-keratinizing (e.g., mesothelial cells). Although not typical endothelial markers, cytokeratins are sometimes present in microvascular endothelial cells.
There are at least 20 cytokeratin types (40–70 kDa, pI 5–8.5) identifiable by two-dimensional gel electrophoresis. CK proteins are divided into two main classes:
- Type I (acidic polypeptides)
- Type II (basic polypeptides)
Each epithelial cell expresses at least one member of each class. Monoclonal antibodies against cytokeratins are valuable tools for tumor identification and classification.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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