Thermo Fisher Scientific Cytokeratin 10 (Suprabasal Epithelial Marker) Monoclonal Antibody (DE-K10)
Cytokeratin 10 단백질을 인식하는 DE-K10 단클론 항체로, 상피세포의 상층부 마커로 사용. IHC(P), IHC(PFA) 등 다양한 면역조직화학 분석에 적합. 사람, 개, 고양이에 반응하며, 단백질 A/G로 정제된 액상 형태로 제공. 연구용 전용 시약.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Cat, Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | DE-K10 |
| Immunogen | Cytoskeletal preparation extracted from human ectocervical epithelium |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage conditions | 4°C, do not freeze |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
Cytokeratins (CK) are intermediate filaments of epithelial cells, found in both keratinizing tissues (e.g., skin) and non-keratinizing cells (e.g., mesothelial cells). Although not a traditional marker for endothelial cells, cytokeratins are also present in some microvascular endothelial cells.
At least 20 different cytokeratins (40–70 kDa, pI 5–8.5) can be identified by two-dimensional gel electrophoresis.
Cytokeratins are classified into two groups:
- Type I: acidic polypeptides
- Type II: basic polypeptides
Each epithelial cell expresses at least one member from each class.
Monoclonal antibodies to cytokeratin proteins are useful markers for tumor identification and classification.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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