Thermo Fisher Scientific TYROBP Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1000

-

Immunoprecipitation (IP)

2-4 µg/mg of protein lysate

-

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant full length protein (Human).

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2211119

Product Specific Information

A suggested positive control is NKp44 positive cells.

Target Information

DAP12 is a transmembrane adaptor protein that is non-covalently associated with several cell surface receptors on natural killer (NK), myeloid, and presumably neuronal cells. DAP12 contains an ITAM domain that preferentially recruits the protein tyrosine kinase Syk to initiate signal transduction. Deficiency of DAP12 results in reduced antigen presentation function by myeloid cells and defects in function of certain NK cell receptors in mice, as well as presenile dementia and bone cysts in humans.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.