Thermo Fisher Scientific Calreticulin Polyclonal Antibody
Western blot 및 ICC/IF에 적합한 Calreticulin 폴리클로날 항체. 인간 Calreticulin C-말단 도메인을 면역원으로 제작. Sheep IgG 호스트, 비결합형 액상 형태로 제공. 단기 4°C, 장기 -20°C 보관 권장.
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- PA131288
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 | - |
| Immunocytochemistry (ICC/IF) | 1:50 | 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Published species | Not Applicable |
| Host / Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | C-terminal domain of human calreticulin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_1957488 |
Product Specific Information
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Calr (Calreticulin) is a calcium-binding chaperone that promotes folding, oligomeric assembly, and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle.
Calr, a lectin, interacts transiently with almost all monoglucosylated glycoproteins synthesized in the ER.
It also interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export.
Additionally, Calr may be involved in maternal gene expression regulation and oocyte maturation through regulation of calcium homeostasis.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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