Thermo Fisher Scientific MSH6 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.5-1 µg/mL

-

Immunocytochemistry (ICC/IF)

10-20 µg/mL

-

Immunoprecipitation (IP)

2.5-5 µg/mL

-

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

synthetic peptide corresponding to amino acids 1311-1327 of human MSH6, conjugated to KLH via an N-terminal added cysteine residue. The immunizing peptide differs from the rat and mouse sequences in one amino acid

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.4 mg/mL

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_1957788

Product Specific Information

Recommended positive controls: HEK 293T, HeLa.

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

The DNA mismatch repair MSH2/MSH6 heterodimer is responsible for the detection of DNA damage, and may promote apoptosis in normal cells, thus protecting mammals from ultraviolet-induced malignant transformation and hence the prevention of skin cancer.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.