Thermo Fisher Scientific MSH6 Polyclonal Antibody
MSH6 단백질을 검출하기 위한 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, ICC/IF, IP 등 다양한 응용에 적합. 고농도(1.4 mg/mL) 액상 형태로 제공되며, 장기 보관 시 -20°C에서 안정적. DNA 손상 감지 연구에 유용.
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Thermo Fisher Scientific MSH6 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–1 µg/mL |
| Immunocytochemistry (ICC/IF) | 10–20 µg/mL |
| Immunoprecipitation (IP) | 2.5–5 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 1311–1327 of human MSH6, conjugated to KLH via an N-terminal added cysteine residue. The immunizing peptide differs from the rat and mouse sequences in one amino acid. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.4 mg/mL |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_1957788 |
Product Specific Information
- Recommended positive controls: HEK 293T, HeLa
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
The DNA mismatch repair MSH2/MSH6 heterodimer is responsible for the detection of DNA damage and may promote apoptosis in normal cells, thus protecting mammals from ultraviolet-induced malignant transformation and the prevention of skin cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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