Thermo Fisher Scientific Lewis A/B Recombinant Mouse Monoclonal Antibody (HEA164)
Lewis A/B 항원을 인식하는 재조합 마우스 단클론 항체로, WB, IHC, ICC/IF, Flow, IP 등 다양한 면역실험에 사용 가능. HEK293 세포에서 발현된 IgM 타입이며 인간 시료에 반응. 암 및 염증 관련 연구용으로 적합.
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Thermo Fisher Scientific Lewis A/B Recombinant Mouse Monoclonal Antibody (HEA164)
Applications and Tested Dilution
- Western Blot (WB): Assay-dependent
- Immunohistochemistry (IHC): Assay-dependent
- Immunocytochemistry (ICC/IF): Assay-dependent
- Flow Cytometry (Flow): Assay-dependent
- Immunoprecipitation (IP): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgM, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | HEA164 |
| Immunogen | This antibody was raised by immunising mice with human carcinoma cells. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
Product Specific Information
This antibody is specific for Lewis a,b carbohydrate antigens.
Target Information
Lewis A and Lewis B are fucose-containing carbohydrates expressed on the surface of red blood cells and other tissues. These antigens are part of the Lewis family, involved in immune recognition, cell adhesion, and inflammation.
Their expression is determined by the FUT3 gene, encoding fucosyltransferase. Individuals with FUT3 mutations express Lewis A but not Lewis B, and vice versa. Some may be Lewis negative due to FUT2 gene mutations.
Lewis antigen presence or absence can influence disease susceptibility and cancer progression by modulating immune responses and tumor metastasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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