Thermo Fisher Scientific Cytomegalovirus gH Late Antigen Recombinant Mouse Monoclonal Antibody (HCMV16)

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

Assay-dependent

-

ELISA (ELISA)

Assay-dependent

-

Immunoprecipitation (IP)

Assay-dependent

-

Neutralization (Neu)

Assay-dependent

-

Product Specifications

Species Reactivity

Virus

Host/Isotype

Mouse / IgG1, kappa

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

HCMV16

Immunogen

The original antibody was generated by immunization of mice with purified HCMV strain AD169.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS

Contains

0.02% ProClin 300

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

Product Specific Information

This antibody binds gpUL75 (gH) of the human cytomegalovirus, which is an 86-kDa glycoprotein. The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. It is though to bind a conformational epitope on the gH, and its bind is destroyed if the protein is denatured.

Target Information

Cytomegalovirus is an enveloped double stranded DNA virus which in humans (HCMV) is commonly known as human herpesvirus 5 (HHV-5). Cytomegalovirus glycoprotein H (gH) late neutralizing antigen and reacts with MRC-5 infected cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.