Thermo Fisher Scientific CD41/CD61 Recombinant Mouse Monoclonal Antibody (10E5)

Applications

Tested Dilution

Publications

Western Blot (WB)

Assay-dependent

-

Immunocytochemistry (ICC/IF)

Assay-dependent

-

ELISA (ELISA)

Assay-dependent

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2a, kappa

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

10E5

Immunogen

Human blood platelets. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CD41/CD61,uniProtId:P08514-1,ncbiNodeId:9606,antigenRange:1-1039,antigenLength:1039,antigenImageFileName:MA5-51800_CD41CD61_P08514-1_House_mouse.svg,antigenImageFileNamePDP:MA5-51800_CD41CD61_P08514-1_House_mouse_PDP.jpeg,sortOrder:1},{targetFamily:CD41/CD61,uniProtId:P05106-1,ncbiNodeId:9606,antigenRange:1-788,antigenLength:788,antigenImageFileName:MA5-51800_CD41CD61_P05106-1_House_mouse.svg,antigenImageFileNamePDP:MA5-51800_CD41CD61_P05106-1_House_mouse_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS

Contains

0.02% ProClin 300

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

Product Specific Information

The antibody binds to GPIIb/IIIa with an affinity (Kd) of 16.2±6 nM. The antibody completely inhibits platelet aggregation at 7.8 µg/mL.

Target Information

CD41 is a transmembrane glycoprotein (integrin family) composed of two chains GPIIb alpha (heavy chain; 120 kDa) and GPIIb beta (light chain; 23 kDa). CD61 non-covalently associates with CD41.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.