Thermo Fisher Scientific PSG1 Monoclonal Antibody (06)

Applications

ELISA (ELISA)

• Tested Dilution: 1:1,000–1:2,000
• Publications: N/A

Product Specifications

Product Specific Information

This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody shows specificity for Human PSG1/PS-beta-G-1.

Target Information

Human pregnancy-specific glycoproteins (PSG) are a group of closely related secreted glycoproteins highly expressed in placental syncytiotrophoblast cells of fetal origin.
PSG are commonly expressed in tumors of trophoblast origin such as hydatidiform mole and choriocarcinoma. They represent the most abundant fetal protein in maternal blood at term.
The eleven human PSG genes (PSG1–PSG11) form, together with the carcinoembryonic antigen (CEA)-related cell adhesion molecule (CEACAM) genes, the CEACAM gene family.
PSG stimulate secretion of TH2-type cytokines from monocytes. CD9 has been identified as the monocyte receptor for murine PSG17.
PSG are thought to modulate the maternal immune system during pregnancy, protecting the semiallotypic fetus from rejection.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.