Thermo Fisher Scientific MMP-24/MT5-MMP Polyclonal Antibody
MMP-24/MT5-MMP 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(P)에서 검증됨. 인간 시료에 반응하며, 항원 친화 크로마토그래피로 정제됨. PBS buffer에 보존되어 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to the C-terminus of human MMP-24 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: Colorectal cancer
- Cellular location: Cell membrane, Secreted
Target Information
All cells within tissues are surrounded by an extracellular matrix (ECM) that provides shape and structure. The ECM is continuously remodeled, maintaining communication between cells. Matrix metalloproteinases (MMPs) are Zn²⁺-binding endopeptidases that degrade ECM components and modulate cell-matrix interactions. They play key roles in tissue remodeling, wound healing, angiogenesis, and tumor invasion. MMP activity is regulated by tissue inhibitors of metalloproteinases (TIMPs), which can act as metastasis suppressor genes by blocking tumor cell invasion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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