Thermo Fisher Scientific CHMP2B Polyclonal Antibody
CHMP2B 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal 항체. Western blot과 ELISA에 적합하며, 인간 및 생쥐 시료에서 반응. Affinity chromatography로 정제된 액상 형태로, -20°C에서 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–213 of human CHMP2B (NP_0547622) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.22 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806503 |
Product Specific Information
Immunogen sequence:
MASLFKKKTV DDVIKEQNRE LRGTQRAIIR DRAALEKQEK QLELEIKKMA KIGNKEACKV LAKQLVHLRK QKTRTFAVSS KVTSMSTQTK VMNSQMKMAG AMSTTAKTMQ AVNKKMDPQK TLQTMQNFQK ENMKMEMTEE MINDTLDDIF DGSDDEEESQ DIVNQVLDEI GIEISGKMAK APSAARSLPS ASTSKATISD EEIERQLKAL GVD
Positive Samples:
MCF7, BT-474, 22Rv1, Lovo, A-549, Mouse lung, Mouse testis, Mouse kidney
Cellular Location:
Cytoplasm, Late endosome membrane, Peripheral membrane protein, cytosol
Target Information
CHMP2B, also known as CHMP2.5 or vacuolar protein-sorting-associated protein 2-2, is a 213 amino acid cytosolic protein. It is widely expressed in brain, heart, skeletal muscle, small intestine, pancreas, lung, placenta, and leukocytes. CHMP2B associates directly with CHMP2A and VPS4 for the disassembly of the ESCRT-III complex.
Defects in the CHMP2B gene have been shown to cause chromosome 3-linked frontotemporal dementia (FTD3).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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