Thermo Fisher Scientific Nectin 2 Polyclonal Antibody
Human Nectin 2 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot 및 ELISA에 적합. 고순도 Affinity Chromatography 정제. PBS/glycerol buffer에 보관되며, 세포막 단백질 연구에 활용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 382–479 of human Nectin 2/CD112 (NP_002847.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.41 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806497 |
Product Specific Information
- Immunogen sequence:
FILLRVRRRR KSPGGAGGGA SGDGGFYDPK AQVLGNGDPV FWTPVVPGPM EPDGKDEEEE EEEEKAEKGL MLPPPPALED DMESQLDGSL ISRRAVYV - Positive Samples: MCF-7, SW620, A-549, SKOV3
- Cellular Location: Cell membrane, Single-pass type I membrane protein
Target Information
This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. It is a component of adherens junctions in the plasma membrane and serves as an entry receptor for certain mutant strains of herpes simplex virus and pseudorabies virus. It is involved in cell-to-cell viral spread, and genetic variations may influence the severity of multiple sclerosis. Alternate splice variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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