Thermo Fisher Scientific Nectin 2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 382-479 of human Nectin 2/CD112 (NP_0028471) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Nectin 2,uniProtId:Q92692-1,ncbiNodeId:9606,antigenRange:382-479,antigenLength:538,antigenImageFileName:PA5-92433_Nectin_2_Q92692-1_Rabbit.svg,antigenImageFileNamePDP:PA5-92433_Nectin_2_Q92692-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.41 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2806497

Product Specific Information

Immunogen sequence: FILLRVRRRR KSPGGAGGGA SGDGGFYDPK AQVLGNGDPV FWTPVVPGPM EPDGKDEEEE EEEEKAEKGL MLPPPPALED DMESQLDGSL ISRRAVYV; Positive Samples: MCF-7, SW620, A-549, SKOV3; Cellular Location: Cell membrane, Single-pass type I membrane protein

Target Information

This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.