
ELK Biotechnology Ghrelin Receptor rabbit pAb
Ghrelin Receptor를 인식하는 토끼 폴리클로날 항체로, WB, IHC, IF에 사용 가능. 세포막 단백질 검출에 적합하며, 에너지 항상성과 성장호르몬 분비 경로 연구에 활용. -20°C에서 1년 보관 가능.
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Ghrelin Receptor rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Ghrelin Receptor rabbit pAb |
| Alternative Names | Growth hormone secretagogue receptor type 1 (GHS-R; GH-releasing peptide receptor; GHRP; Ghrelin receptor) |
| Applications | WB; IHC; IF |
| Recommended Dilutions | WB 1:1000-2000, IHC 1:100-200 |
| Immunogen | Synthetic Peptide of Ghrelin Receptor (AA range: 290-370) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 41 kD |
| GeneID (Human) | 2693 |
| Human Swiss-Prot No | Q92847 |
| Cellular Localization | Cell membrane; Multi-pass membrane protein |
| Species Reactivity | Human; Rat; Mouse |
Background
This gene encodes a member of the G-protein coupled receptor family. The encoded protein may play a role in energy homeostasis and regulation of body weight. Two identified transcript variants are expressed in several tissues and are evolutionarily conserved in fish and swine.
One transcript (1a) excises an intron and encodes the functional protein; this protein is the receptor for the Ghrelin ligand and defines a neuroendocrine pathway for growth hormone release.
The second transcript (1b) retains the intron and does not function as a receptor for Ghrelin; however, it may function to attenuate activity of isoform 1a. Mutations in this gene are associated with autosomal idiopathic short stature.
[provided by RefSeq, Apr 2010]
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