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ELK Biotechnology c-Myb (Acetyl Lys471) rabbit pAb
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ELK Biotechnology c-Myb (Acetyl Lys471) rabbit pAb

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인간 c-Myb (Acetyl Lys471)에 특이적인 rabbit polyclonal antibody로, WB 및 ELISA에 사용 가능. 핵 내 단백질 검출에 적합하며, 높은 특이성과 안정성을 제공. 1 mg/ml 농도로 제공되며 -20°C에서 1년간 보관 가능.

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pk
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ELK Biotechnology ES20114-100UL c-Myb (Acetyl Lys471) rabbit pAb, 100UL pk판매 단위 pk ·
재고 확인 필요
402,000원VAT 포함 442,200원
ELK Biotechnology ES20114-50UL c-Myb (Acetyl Lys471) rabbit pAb, 50UL pk판매 단위 pk ·
재고 확인 필요
301,000원VAT 포함 331,100원

ELK Biotechnology · ELK Biotechnology c-Myb (Acetyl Lys471) rabbit pAb

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c-Myb (Acetyl Lys471) rabbit pAb

기본 정보

항목 내용
Alternative Names Transcriptional activator Myb (Proto-oncogene c-Myb)
Applications WB; ELISA
Recommended Dilutions WB 1:1000–2000, ELISA 1:5000–20000
Immunogen Synthesized peptide derived from human c-Myb (Acetyl Lys471)
Storage -20°C / 1 year
Host Rabbit
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band 70 kD
GeneID (Human) 4602
Human Swiss-Prot No P10242
Cellular Localization Nucleus
Species Reactivity Human; Mouse

Background

  • Domain: Comprised of 3 domains; an N-terminal DNA-binding domain, a centrally located transcriptional activation domain, and a C-terminal domain involved in transcriptional repression.
  • Function: Transcriptional activator; DNA-binding protein that specifically recognizes the sequence 5'-YAAC[GT]G-3'. Plays an important role in controlling proliferation and differentiation of hematopoietic progenitor cells.
  • PTM: Phosphorylated by NLK on multiple sites, inducing proteasomal degradation. Ubiquitinated by SIAH1, leading to proteasomal degradation.
  • Similarity: Contains 3 HTH myb-type DNA-binding domains.
  • Subunit: Binds MYBBP1A. Interacts with HIPK2, MAF, and NLK.

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