ELK Biotechnology KCNN2 (SK2) rabbit pAb
KCNN2(SK2) 단백질을 인식하는 토끼 폴리클로날 항체로, WB, IHC, IF에 사용 가능. 신경세포 흥분성 조절 연구에 적합하며, 사람, 쥐, 생쥐 시료에 반응. 합성 펩타이드 면역원으로 제작되어 높은 특이성과 재현성을 제공.
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KCNN2 (SK2) Rabbit Polyclonal Antibody
제품 정보
| 항목 | 내용 |
|---|---|
| Product Name | KCNN2 (SK2) rabbit pAb |
| Alternative Names | YM3565 |
| Applications | WB, IHC, IF |
| Recommended Dilutions | WB 1:1000–2000, IHC 1:100–200 |
| Immunogen | Synthetic Peptide of KCNN2 (SK2) |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 70, 26 kDa |
| Gene ID (Human) | 3781 |
| Human Swiss-Prot No. | Q6PJI0 |
| Cellular Localization | Smooth endoplasmic reticulum, plasma membrane, cell surface, integral component of membrane, Z disc, T-tubule, neuronal cell body, dendritic spine |
| Species Reactivity | Human, Rat, Mouse |
Background
Potassium calcium-activated channel subfamily N member 2 (KCNN2) is a human gene encoding a protein involved in regulating neuronal excitability. In vertebrate neurons, action potentials are followed by an afterhyperpolarization (AHP) that can last for several seconds, influencing neuronal firing patterns. Each AHP component is mediated by distinct calcium-activated potassium channels. The KCNN2-encoded protein contributes to the slow component of synaptic AHP and forms a voltage-independent, calcium-activated channel with calmodulin-binding subunits. This gene belongs to the KCNN family, and alternative splicing results in multiple transcript variants. (RefSeq, May 2013)
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