ELK Biotechnology Histone H2A.Z (Acetyl Lys7) rabbit pAb
Histone H2A.Z (Acetyl Lys7)에 특이적인 rabbit polyclonal antibody로, WB에 적합합니다. 핵 및 염색체에 위치한 H2A.Z 단백질 검출에 사용되며, 고품질 합성 펩타이드로 면역생성되었습니다. -20°C에서 1년간 안정적으로 보관 가능합니다.
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Histone H2A.Z (Acetyl Lys7) rabbit pAb
제품 개요
Histone H2A.Z (Acetyl Lys7)에 대한 rabbit polyclonal antibody로, 진핵세포의 핵 내 염색체 구조 연구에 활용됩니다. 합성 펩타이드를 면역원으로 제작되었으며, Western blot(WB) 분석에 적합합니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Histone H2A.Z (Acetyl Lys7) rabbit pAb |
| Alternative Names | H2AFZ; H2AZ; Histone H2A.Z; H2A/z |
| Applications | WB |
| Recommended Dilutions | WB: 1:500–1000 |
| Immunogen | Synthetic Peptide of Histone H2A.Z (Acetyl Lys7) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Observed Band | 14 kD |
| GeneID (Human) | 3015 |
| Human Swiss-Prot No | P0C0S5 |
| Cellular Localization | Nucleus, Chromosome |
| Species Reactivity | Human, Mouse, Rat |
Background
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fibers in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of linker histone H1 with DNA between nucleosomes to form higher-order chromatin structures. This gene encodes a replication-independent member of the histone H2A family, distinct from other family members. Studies in mice have shown that this histone is required for embryonic development and that lack of functional histone H2A leads to embryonic lethality.
(Provided by RefSeq, Jul 2008)
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