Thermo Fisher Scientific Calreticulin Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:300-1:500

-

Immunohistochemistry (Frozen) (IHC (F))

1:50-1:70

-

Immunocytochemistry (ICC/IF)

-

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Product Specifications

Published species

Virus

Host/Isotype

Goat / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Purified rabbit skeletal muscle calreticulin

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_1954684

Product Specific Information

Store as a concentrated solution. Centrifuge briefly prior to opening vial.

Target Information

Calr or Calreticulin is a calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. Calr, a lectin, interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Calr also interacts with with the DNA-binding domain of NR3C1 and mediates its nuclear export. It may also be involved in maternal gene expression regulation and oocyte maturation via the regulation of calcium homeostasis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.