Thermo Fisher Scientific AIMP1/EMAPII/SCYE1 Polyclonal Antibody
AIMP1/EMAPII/SCYE1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, IP 등 다양한 응용에 적합. 액상 형태, 1 mg/mL 농도, 4°C 보관. 세포 사멸 관련 사이토카인 연구에 활용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:2,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 262–312 of human Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 (Multisynthase complex auxiliary component p43). Cleaved into: Endothelial monocyte-activating polypeptide 2 (EMAP-2), EMAP-II, Small inducible cytokine subfamily E member 1. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Application Note: For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections.
Target Information
The protein encoded by this gene is a cytokine specifically induced by apoptosis and involved in angiogenesis, inflammation, and wound healing. Its release renders tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein corresponds to the p43 subunit of the multi-tRNA synthetase complex and modulates aminoacylation activity of tRNA synthetase in normal cells. It also stimulates inflammatory responses after proteolytic cleavage in tumor cells. Multiple transcript variants and a pseudogene on chromosome 20 have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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