Thermo Fisher Scientific AIMP1/EMAPII/SCYE1 Polyclonal Antibody
AIMP1/EMAPII/SCYE1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot, IHC, IP 등 다양한 응용에 적합하며, 항원 친화 크로마토그래피로 정제됨. 4°C 보관, 1년 권장 유효기간.
- 카탈로그번호
- A304896A
- 판매단위
- pk
카탈로그
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:2,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 262–312 of human Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 (Multisynthase complex auxiliary component p43), cleaved into Endothelial monocyte-activating polypeptide 2 (EMAP-2) / SCYE1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections.
Target Information
The encoded protein is a cytokine specifically induced by apoptosis, involved in the regulation of angiogenesis, inflammation, and wound healing. Its release sensitizes tumor-associated vasculature to tumor necrosis factor. The precursor protein corresponds to the p43 subunit of the multi-tRNA synthetase complex, modulating aminoacylation activity in normal cells. After proteolytic cleavage in tumor cells, it stimulates inflammatory responses. Multiple transcript variants and a pseudogene on chromosome 20 have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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