Thermo Fisher Scientific Synapsin 1 Monoclonal Antibody (M365)
Synapsin I 단백질을 검출하는 Mouse monoclonal antibody (Clone M365). WB 및 ICC/IF에 적합하며 인간, 마우스, 랫트 시료 반응. 고순도 Protein A 정제, 액상형, -20°C 보관. 신경세포 시냅스 형성 및 신경전달 연구에 활용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:50
- Publications: [References not provided]
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:1,000
- Publications: [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | M365 |
| Immunogen | Clone M365 was generated from a sequence corresponding to amino acids in the C-terminal region of mouse synapsin I. This sequence has high homology to human and rat synapsin I. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.04 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 1 mg/mL BSA, 50% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2942662 |
Product Specific Information
This antibody detects an 80 kDa protein corresponding to the molecular mass of Synapsin I on SDS-PAGE immunoblots of adult mouse brain.
Target Information
SYN1 (synapsin 1) is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins associated with the cytoplasmic surface of synaptic vesicles. They are involved in synaptogenesis and modulation of neurotransmitter release, suggesting roles in neuropsychiatric diseases. Synapsin 1 regulates axonogenesis and synaptogenesis and serves as a substrate for multiple protein kinases. Mutations may be linked to X-linked neuronal degeneration disorders such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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