Thermo Fisher Scientific MCM2 Monoclonal Antibody (2B3)
MCM2 단백질을 검출하는 Mouse Monoclonal Antibody (Clone 2B3). Western blot, IHC, Flow cytometry 등 다양한 응용에 사용 가능. Human, Mouse, Rat, Non-human primate 시료에 반응. 연구용 전용 제품으로 DNA 복제 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | View 1 publication |
| Immunohistochemistry (IHC) | – | View 2 publications |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200–1:1,000 | View 1 publication |
| Immunocytochemistry (ICC/IF) | – | View 1 publication |
| Flow Cytometry (Flow) | 1:200–1:400 | – |
| ELISA | 1:10,000 | – |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Published Species | Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2B3 |
| Immunogen | Purified recombinant fragment of human MCM2 expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11155194 |
Product Specific Information
MA5-15895 targets MCM2 in indirect ELISA, FACS, IHC, and WB applications, showing reactivity with Human, Mouse, Non-human primate, and Rat samples.
The immunogen is a purified recombinant fragment of human MCM2 expressed in E. coli.
MA5-15895 detects MCM2, which has a predicted molecular weight of approximately 125 kDa.
Target Information
MCM2 (Mini Chromosome Maintenance Protein 2) plays a key role in regulating DNA replication.
Also known as CDCL1, Mitotin, and BM28, MCM2 is a nuclear protein critical for the onset of DNA replication and cell division.
It is part of the early S-phase protein family and has been mapped to chromosome 3q21.
Due to its genomic localization, CDCL1 is considered a potential oncogene implicated in chromosomal breaks observed in acute myeloid leukemia (AML).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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