Thermo Fisher Scientific Crk Monoclonal Antibody (3G11E8)
Crk 단백질을 검출하기 위한 Thermo Fisher Scientific의 단클론 항체로, WB, IHC, ICC/IF, Flow Cytometry, ELISA 등 다양한 응용 가능. 인간 및 마우스 반응성, IgG2b 아이소타입, 비결합형 액상 형태. 연구용으로만 사용.
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Thermo Fisher Scientific Crk Monoclonal Antibody (3G11E8)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:200–1:1,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3G11E8 |
| Immunogen | Purified recombinant fragment of human CRK expressed in E. Coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_11153760 |
Product Specific Information
MA5-15892 targets CRK in indirect ELISA, FACS, IF, IHC, and WB applications and shows reactivity with Human samples.
The MA5-15892 immunogen is purified recombinant fragment of human CRK expressed in E. coli.
MA5-15892 detects CRK with a predicted molecular weight of approximately 42 kDa.
Target Information
Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I.
Crk-II mediates attachment-induced MAPK8 activation, membrane ruffling, and cell motility in a Rac-dependent manner.
Involved in phagocytosis of apoptotic cells and cell motility via interaction with DOCK1 and DOCK4.
May regulate EFNA5-EPHA3 signaling.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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