Thermo Fisher Scientific FOS Monoclonal Antibody (UMAB221), UltraMAB
인간 FOS 단백질을 인식하는 UMAB221 클론의 마우스 모노클로날 항체로, WB, IHC(P), ChIP 등 다양한 연구용 분석에 사용 가능. 고순도 친화 크로마토그래피 정제, 액상 형태, 안정적인 저장 및 운송 조건 제공.
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Thermo Fisher Scientific FOS Monoclonal Antibody (UMAB221), UltraMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:200 |
| ChIP assay (ChIP) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | UMAB221 |
| Immunogen | Full length human recombinant protein of human FOS produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.0 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
FBJ murine osteosarcoma viral oncogene homolog, commonly known as Cellular protooncogene Fos (c-Fos), belongs to the Fos transcription factor family and is encoded by the C-FOS gene located on chromosome 14.
c-Fos heterodimerizes with c-Jun to form the Activator Protein-1 (AP-1) transcription factor, which regulates transcription of genes involved in signal transduction, cell proliferation, and differentiation.
It is phosphorylated by various stimuli, including growth factors and insulin, at multiple sites. The upstream kinase ERK MAPK phosphorylates c-Fos at Threonine 232, regulating its nuclear localization and transcriptional activity.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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