Thermo Fisher Scientific FOS Monoclonal Antibody (UMAB221), UltraMAB

Thermo Fisher Scientific FOS Monoclonal Antibody (UMAB221), UltraMAB

Applications and Tested Dilution

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

FBJ murine osteosarcoma viral oncogene homolog, known as Cellular proto-oncogene Fos (c-Fos), belongs to the Fos transcription factor family and is encoded by the C-FOS gene on chromosome 14.
c-Fos forms a heterodimer with c-Jun to create the Activator Protein-1 (AP-1) transcription factor, which regulates genes involved in signal transduction, cell proliferation, and differentiation.
It is phosphorylated at multiple sites by various stimuli, including growth factors and insulin. ERK MAPK is a key kinase responsible for phosphorylation at Threonine 232, influencing c-Fos nuclear localization and transcriptional activity.

For Research Use Only. Not for use in diagnostic procedures or resale without authorization.