Thermo Fisher Scientific FOS Monoclonal Antibody (UMAB221), UltraMAB
인간 FOS 단백질을 인식하는 UMAB221 클론의 마우스 모노클로날 항체. Western blot, IHC, ChIP, Peptide Array 등 다양한 실험에 사용 가능. 고순도 친화 크로마토그래피 정제, 동결건조 형태로 제공. 연구용으로만 사용.
- 카탈로그번호
- UM800113CF
- 판매단위
- pk
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Thermo Fisher Scientific FOS Monoclonal Antibody (UMAB221), UltraMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:200 |
| ChIP assay (ChIP) | Assay-dependent |
| Peptide Array (Array) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | UMAB221 |
| Immunogen | Full-length human recombinant FOS protein produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
FBJ murine osteosarcoma viral oncogene homolog, known as Cellular proto-oncogene Fos (c-Fos), belongs to the Fos transcription factor family and is encoded by the C-FOS gene on chromosome 14.
c-Fos forms a heterodimer with c-Jun to create the Activator Protein-1 (AP-1) transcription factor, which regulates genes involved in signal transduction, cell proliferation, and differentiation.
It is phosphorylated at multiple sites by various stimuli, including growth factors and insulin. ERK MAPK is a key kinase responsible for phosphorylation at Threonine 232, influencing c-Fos nuclear localization and transcriptional activity.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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